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下呼吸道重开的生物流体力学研究:实验模拟 被引量:1

BIOFLUID MECHANICS INVESTIGATION ON OBSTRUCTED PULMONARY LOWER AIRWAY REOPENING: EXPERIMENT SIMULATION
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摘要 实验模拟了受阻塞肺下呼吸道重开的生物力学问题。呼吸道模型是玻璃直圆管 ,以具有生物流体性质的机油作为阻塞液。实验给出了在压强差作用下阻塞液柱前阵面以及穿入粘液柱气泡前阵面的位置和速度曲线。结果表明 ,它们受外加压强 ,管直径 ,阻塞液粘度以及初始阻塞液长度的影响。较高的外加压强、阻塞液粘度较低和管径较粗有利于呼吸道的重开。 The reopening of obstructed pulmonary lower airway was simulated experimentally in this paper. A circular rigid glass tube was used as the airway, and Newtonian motor oil the lining liquid. Curves of the positions and velocities of obstructed liquid front and gas bubble front under the dfference of compressed pressure were obtained. The results show that the speed of airway reopening was dependent on various parameters such as reopening pressure, tube inner diameter, and viscosity and initial length of lining liquid. A higher pressure of compressed gas is needed to reopen the obstructed airway and obstructed airways with lower viscosity lining liquid as well as larger diameter were easily reopened.
出处 《生物物理学报》 CAS CSCD 北大核心 2000年第2期380-386,共7页 Acta Biophysica Sinica
关键词 受阻塞肺下呼喊道 生物流体力学 重开机理 Obstructed pulmonary lower airway Reopen Experiment simulation
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参考文献11

  • 1[1]Kamm,R. O.,Schreter,R. C. Is airway closure caused by liquid film instability? Respir.physical.,1989,75:141-156
  • 2[2]Otis,D. R.,Johnson,M.,Pedley,T. J.,et al. Role of pulmonary surfactant in airway closure: a computational study. J. Appl. physiol.,1993,75(3):1323-1333
  • 3[3]Hughes,J. M. B.,Rosenzweig,D. Y.,Kivitz,P. B. Site of airway closure in excised dog lungs:histologic demonstration. J. Appl. physiol.,1970,29:340-344
  • 4[4]Halpern,D.,Grotberg,J. B. Surfactant effects on fluid-elastic instability of liquid-lined flexible tube:a model of airway closure. ASME J. Biomech. Engr.,1993,115:271-277
  • 5[5]Saffman,P. G.,Talor,G. I. The penetration of a fluid into a porous medium or Hale-show cell containing a more viscous liquid. Proc. R. Soc. Lond. A. Math. Phys. sci.,1958,245:312-329
  • 6[6]Talor,G. I. Deposition of a viscous fluid on the wall of a tube. J. fluid Mech.,1961,10:161-165
  • 7[7]Gaver,D. P.,Samsel,R. W.,Sdway,J. Effect of surface tension and viscosity on airway reopening.J. Appl. physiol.,1990,69(1):74-85
  • 8[8]Clarke,S. W.,Pavid,D. Mucociliary Clearance,in: Crystal,R. G. and West,J. B.,eds.,The Lung: Scientific Foundations. Raven,NewYork,1991,1845-1859
  • 9[9]Low,H. T,Chew,Y. T.,Zhou,C. W. Pulmonary airway reopening : effects of non-Newtonian fluid viscosity. ASME J. Biomech. Engr.,1997,119:298-308
  • 10[10]Gaver,D. P.,Halpern,D.,Jensen,O. E.,et al. The steady motion of a semi-infinite bubble through a flexible-walled channel. J. Fluid Mech.,1996,319:25-65

同被引文献2

  • 1Low H T,ASME J Biomech Eng,1997年,119卷,298页
  • 2HUZYAK P C,J Non-Newtonian Fluid Mech,1997年,71卷,73页

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