伴有自杀观念的抑郁障碍与广泛性焦虑障碍条件负变化的比较研究

COMPARATIVE STUDY OF CONTINGENT NEGATIVE VARIATION ACCOMPANYING SUICIDAL IDEA IN PATIENTS WITH DEPRESSION DISORDER(DD) AND PATIENTS WITH GENERALIZED ANXIETY DISORDER (GAD)

目的:探讨伴有自杀观念的抑郁障碍(DD)和广泛性焦虑(GAD)患者条件负变化(CNV)的特点。方法:应用美国NicoletBravo脑诱发电位仪,对59例DD组、42例GAD组和54名正常人(NC组)的CNV作了检测。结果:与正常对照组比较,DD患者CNV的M1波幅降低,PINV出现率高。与此,GAD组的CNV的M1波幅变化方向及PINV出现率与DD一致。结论:CNV应用可作为DD和GAD患者临床应用检测指标。

Objective：To investigate the characteristics of contingent negative variation（CNV） in patients with depression disorder（DD） and generalized anxiety disorder（GAD）. Methods：Using Nicolet Bravo instruments, the CNV was elicited from 59 patients with DD,42 patients with GAD and 54 normal controllers. Results：Compared with NC group, DD group showed decreased M1 amplitude （P0.05）, and GAD group also showed decreased M1 amplitude. Conclusion：Use of CNV can be used for detecting of DD and GAD.