摘要
In order to improve the wettability and biocompatibility of the poly (butylene terephthalate) non-woven (PBTNW), the method of surface modification is used to graft copolymerization of chitosan (CS) onto the PBTNW under alkylpolyglycoside (APG) inducing. The product is thoroughly characterized with the Fourier transform infrared spectroscopy (FrIR), the electron spectroscopy for chemical analysis (ESCA), the thermogravimetric (TG) and the scanning electron microscopy (SEM). It is found that chitosan is successfully grafted onto PBTNW. In addition, the water contact angles, hemolysis tests and cytotoxicity evaluation tests show an improvement in wettability and biocompatihility as a result of graft copolymerization of chitosan. So the CS-grafted PBTNW exhibits greater superiority than the original PBTNW. The CS-grafted PBTNW can be a candidate for blood filter materials and other medical applications.
为了提高聚对苯二甲酸丁二醇酯非织造布(PBTNW)的亲水性和生物相容性,采用表面改性的方法,在烷基糖苷(APG)的引导作用下将壳聚糖(CS)通过共聚接枝修饰到PBTNW的表面.利用傅里叶全反射红外光谱(FTIR)分析仪、化学分析电子光谱学(ESCA)检测仪、热重(TG)分析仪及扫描电镜(SEM)对修饰前后的PBTNW材料进行表征,发现壳聚糖被成功接枝到PBTNW表面.此外,对修饰前后的PBTNW进行水接触角、溶血率和细胞毒性实验,结果表明壳聚糖接枝后的PBTNW具有良好的亲水性和生物相容性.接枝后的PBTNW较接枝前更具优越性,在血液过滤材料及其他的药用领域都可能是一种很好的替补材料.