布地奈德联合沙丁胺醇溶液雾化吸入控制哮喘急性发作的疗效观察

The effects of aerosol inhalation of budesonide combined with salbutamol solution on asthma acute attack

目的观察布地奈德混悬液联合沙丁胺醇溶液雾化吸入控制儿童哮喘急性发作的疗效。方法将76例哮喘急性发作患儿随机分为两组,治疗组(38例)在常规抗菌药物及对症治疗基础上采用布地奈德混悬液联合沙丁胺醇溶液通过雾化吸入,对照组(38例)采用常规抗菌药物及对症治疗。治疗一周后观察比较两组疗效。结果治疗后咳嗽、喘息、紫绀、啰音等症状与体征的持续时间治疗组明显短于对照组,差异有统计学意义(P<0.05);总有效率治疗组为97.4%,对照组为84.2%,两组比较差异有统计学意义(P<0.05)。结论采用布地奈德混悬液联合沙丁胺醇溶液通过雾化吸人治疗哮喘急性发作,疗效显著。

Objective To observe the effects of aerosol inhalation of budesonide combined with salbutamol solution on asthma acute attack in children.Method 76 cases of acute episode of asthma were randomly divided into two groups.The experiment group（38 cases） were treated with aerosol inhalation of budesonide combined with salbutamol solution in addition to the use of conventional antimicrobial agents and symptomatic treatment.The control group（n=38） were treated with conventional antimicrobial agents and symptomatic treatment only.One week after therapy effects of the medicine were observed in two groups.Results After treatment,the duration of cough,wheezing,cyanosis,rales,and symptoms in the treatment group was significantly shorter than that in the control group.The difference was statistically significant（P0.05）;the total effective rate in the treatment group was 97.4%,and 84.2% in the control group.There was significant difference between two groups（P0.05）.Conclusion Aerosol inhalation of budesonide combined with salbutamol solution in treating acute asthma attack appeared to have curative effect.