阿奇霉素联合盐酸洛美沙星治疗非淋菌性尿道炎的临床研究

Clinical study on azithromycin combined with hydrochloric acid lomefloxacin in treatment of non-gonococcal urethritis inflammation

目的为提高临床治愈率,了解阿奇霉素联合盐酸洛美沙星治疗非淋菌性尿道(宫颈)炎的临床应用价值。方法选择2009年1月-2011年12月接受治疗的200例患者,将其随机分为观察组和对照组,每组各100例;对照分析两组临床疗效、病原学清除、总疗效及不良反应。结果观察组治愈率85.0%、显效率7.0%,显著高于对照组的54.0%、14.0%;观察组病原体全清除率94.0%,显著高于对照组的72.0%,两组差异均有统计学意义(P<0.05)。结论阿奇霉素联合盐酸洛美沙星治疗非淋菌性尿道(宫颈)炎,临床疗效好,病原体清除率高,值得临床推广使用。

OBJECTIVE To study the clinical value of azithromycin combined with hydrochloric acid iomefloxacin in treatment of non-gonococcal urethritis （cervicitis） inflammation. METHODS A total of 200 patients who were treated in the hospital from Jan 2009 to Dec 2011 were selected as the objects and were randomly divided into the observation group and the control group with 100 cases in each. The clinical efficacy, clearance of etiology, total efficacy,and the adverse reactions of the two groups were compared and analyzed. RESULTS The cure rate of the observation group was 85. 0%, markedly effective rate 7. 0%, which were significantly higher than 54. 0%, 14.0% in the control group （P〈0. 05）. The complete clearance rate of the pathogens was 94. 0% in the observation group,significantly higher than 72.0% in the control group, the differences between the two groups were statistically significant （P 〈 0. 05 ）. CONCLUSION Azithromycin combined with hydrochloric acid lomefloxacin is effective in treatment of non-gonococcal urethritis （cervicitis） inflammation with good clinical efficacy and high clearance rate of pathogens, which thus is worthy of being promoted in the hospital.