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达英-35联合二甲双胍治疗多囊罗19巢综合征30例 被引量:14

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摘要 目的观察达英-35联合二甲双胍治疗多囊卵巢综合征(PCOS)的临床疗效。方法将60例PCOS患者随机分为观察组及对照组,各30例,观察组口服达英一35和二甲双胍,对照组单用达英-35,疗程均为3个月。观察两组治疗后症状改善情况及不良反应;检测治疗前后促卵泡生成激素(FSH)、促黄体生成素(LH)、LH/FSH、雌二醇(E2)、睾酮(T)、空腹三酰甘油(TG)、空腹血糖(FBG)、胰岛素(INS)、体质量指数(BMI)、腰臀比(WHR)。结果观察组症状改善,且大部分患者体质量减轻,无明显不良反应。观察组LH、LH/FSH、T、TG、INS、BMI、WHR明显低于治疗前,TG、INS、BMI、WHR明显低于对照组(P〈0.05);对照组LH、LH/FSH、T明显低于治疗前(P〈0.05)。结论达英-35联合二甲双胍能从病理生理上控制引起PCOS的根源.治疗效果明显优于单用达英-35。
出处 《中国实用医刊》 2013年第2期87-88,共2页 Chinese Journal of Practical Medicine
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