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多西紫杉醇联合顺铂及5-氟尿嘧啶治疗胃癌临床观察 被引量:3

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摘要 目的探讨多西紫杉醇、紫杉醇联合顺铂、5-氟尿嘧啶(5-FU)治疗胃癌临床疗效。方法 2008年3月至2011年3月收治的符合入选标准晚期胃癌患者96例,依据治疗方法不同分为多西紫杉醇组50例,紫杉醇组46例;观察两组临床疗效及不良反应。结果两组患者均完成2个周期化疗,按照按WHO实体瘤疗效评价标准[2]进行评价,多西紫杉醇组总有效24例(48.00%),紫杉醇组总有效46例(45.65%),经统计学分析,差异无统计学意义(P>0.05)。结论在晚期胃癌化疗中应用紫杉醇、多西紫杉醇联合顺铂、5-FU方案均能够取得较为良好的临床效果,安全性相差不大,可以作为患者依据经济条件选取方案。
作者 陈淑娟
出处 《临床医学》 CAS 2012年第12期54-55,共2页 Clinical Medicine
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  • 1冯继锋,陆建伟,孙小峰.氟尿嘧啶/亚叶酸钙+紫杉醇联合化疗双周方案治疗晚期胃癌[J].癌症,2004,23(12):1704-1706. 被引量:14
  • 2Schipper DL, Wagener DJT. Chemotherapy of gastric cancer[ J ]. Auticancer Drugs, 1996,7 (2) : 137-149.
  • 3Seymour MT, Dent JT, Papamiehael D, et al. Epirubicin,cisplatin and oral UFT with leueovorin ( ' ECU' ) : A phase I-II study in patients with advanced upper gastrointestinal tract cancer [ J ]. Ann Oncolo, 1999,10 ( 11 ) : 1329-1333.
  • 4Kim YH, Kim BS, Seo JH, et al. Epirubicin, cisplatin, oral UFT, and calcium folinate in advanced gastric carcinoma [ J ].Oncology (Huntingt) , 1999, 13(7 Suppl 3 ) :64-68.
  • 5Macdonald JS, Schein P, Woolley P, et al. 5 '-fluorouracil,doxorubicin, and mitomycin (FAM) combination chemotherapy for advanced gastric cancer [ J ]. Ann Intl Med, 1980,93 ( 4 ) :533-536.
  • 6Wils J. The treatment of advanced gastric cancer [ J ]. Semin Oncolo, 1996,23(3) :397-406.
  • 7Clark JL, Kucuk O, Benson A, et al. Phase Ⅱ trial of etoposide,doxorubicin, and cisplatin combination in advanced measurable gastric cancer. An Eastern Cooperative Oncology Group Study[J] .Am J Clin Oncology ,1995,18(4) :318-324.
  • 8Cervantes A, Villar-Grimalt A, Abad A, et al. 5-Fluorouracil,folinic acid, epidoxorubicin and cisplatin (FLEP) combination chemotherapy in advanced measurable gastric cancer. A phase Ⅱ trial of the Spanish Cooperative Group for Gastrointestinal Tumor Therapy (TTD) [ J]. Ann Oncology, 1993,4(9 ) :753-757.
  • 9Bamias A, Hill ME, Cunningham D, et al. Epirubiein,eisplatin, and protracted venous infusion of 5'-fluorouracil for esophagogastric adenocarcinoma: response, toxicity, quality of life and survival[ J]. Cancer, 1996,77(10) : 1978-1985.
  • 10Findlay M, Cunningham D, Norman A, et al. A phase Ⅱ study in advanced gastroesophageal cancer using epirubicin and cisplatin in combination with continuous infusion 5'-fluorouracil(ECF) [J] .Ann Oncology,1994,5(7) :609-616.

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