慢性髓系白血病相关抗原的研究进展

Recent advances on associated antigens of chronic myeloid leukemia

慢性髓系白血病（CML）是一种起源于造血干细胞的恶性增生性疾病，目前仍缺乏有效的根治方法。联合治疗以提高患者免疫功能状态以及免疫治疗以重建患者免疫功能，是CML比较理想的治疗方法。因此，寻找合适的CML相关性抗原，研究其特异性淋巴细胞，是CML免疫相关治疗的基础。

Chronic myeloid leukemia （CML） is one of myeloid malignancies, and there is no effective treatment method at present. Nowaday, many studies report that combined treatment and adoptive immunotherapy can rebuild immunological function of patients, it＇s an ideal method of cure CML. So searching optimal leukemia-associated antigens and researching the number of antigen specific T lymphocytes is the key to treat CML.