期刊文献+

生物制造技术及发展 被引量:9

The development of biofabrication technology
下载PDF
导出
摘要 自20世纪90年代西安交通大学机械工程学院提出生物制造的概念,提出以工程方法解决医学问题以来,在20多年与医学、材料和生物学等学科专家的密切合作中,已在骨与关节、肝脏、肠道、大脑等器官的人工内植入物研究上取得了进展。重点介绍和总结了定制化人工假体、活性人工骨和关节以及组织工程化肝脏等制造技术的研究工作与成果,探索其中的问题与发展前景。 The concept of biofabrication was provided by School of Mechanical Engineering, Xi' an Jiaotong University since the 1990s. Using the engineering methods to solve the medical issues, we have made some achievements and development on the implants for bone and cartilage, liver, intestinal tissue as well as brain. This paper emphasized on the lastest research work of the customized artificial prosthesis, bioactive bone and joint, and tissue engineered liver in our laboratory, which was corporated with the experts and sciencists of various areas from medicine, biology as well as materials for more than 20 years. Furthermore, it also explored the problems and prospects for the development and application of biofabrication.
出处 《中国工程科学》 北大核心 2013年第1期45-50,共6页 Strategic Study of CAE
基金 国家自然科学基金项目(50775178 51075320) 英国皇家工程协会英中合作项目(2011)
关键词 生物制造 快速成型 功能仿生 骨与关节 组织工程化肝脏 biofabrication prototyping bionic functionality bone and joint tissue engineered liver
  • 相关文献

参考文献25

  • 1北京中研纵横经济信息中心.2011-2015年中国人工关节市场调查及投资前景价值战略规划预测报告[R],2009.
  • 2Langer R,Vacanti J P. Tissue engineering[J].{H}SCIENCE,1993.920-926.
  • 3李涤尘;刘葳;康利轲.促进骨改建的定制化柔性钛下颌骨替代物及其制备方法[P],ZL20071001836572001.
  • 4刘葳,李涤尘,周丽斌,康利轲,王晓聪.定制化柔性下颌骨钛替代物的有限元优化分析及动物试验[J].机械工程学报,2010,46(5):133-138. 被引量:7
  • 5Singare S,Lian Q,Li D. Rapid prototyping assisted sur gery planning and custom implant design[J].Rapid Prototyping Jour-nal,2009,(15):19-23.
  • 6Lian Q,Li D,Lu Z. Customized titanium prostheses incor-porated with autologous fibula for the treatment of whole mandib-ular bone resorption:A successful case report[A].USA:Philadelphia,2010.
  • 7刘晓华;连芩;李涤尘.人工髋关节假体耦合系统承载曲面定制化设计及应力分析[A]{H}北京,2010.
  • 8王臻,滕勇,李涤尘,刘非,郭征,孙峥,李智,李明全,王海强,宦怡,龚雪鹏.基于快速成型技术的个体化人工股骨髁关节面的设计与应用[J].中华外科杂志,2004,42(12):746-749. 被引量:19
  • 9Lian Q,Sun Y,Li D. Design and analysis of bipolar semi-knee prosthesis for better biotribological performance[A].UK:Leeds,2010.
  • 10革军,赵一桐,刘鹏,王臻,李涤尘,连芩,靳忠民.二代定制化双动半膝关节假体的设计及其韧带附丽相关的研究[J].科学技术与工程,2011,11(9):1929-1934. 被引量:5

二级参考文献63

共引文献35

同被引文献60

  • 1魏大忠,张人佶,吴任东,周浩颖.压电驱动微滴喷射过程的数学模型[J].中国机械工程,2005,16(7):611-614. 被引量:18
  • 2Miranda P, Pajares A, Guiberteau F. Finite element modeling as a tool for predicting the fracture behavior of robocast scaffolds. Acta Bioma- ter, 2008, 4(6): 1715-1724.
  • 3Wu Q, Zhang XL, Wu B, et al. Fabrication and characterization of porous HA/D-TCP scaffolds strengthened with micro-ribs structure. Materials Letters, 2013, 92: 274-277.
  • 4Best SM, Porter AE, Thian ES, et al. Bioceramics: Past, present and for the future. J Eur Ceram Soc, 2008, 28(7): 1319-1327.
  • 5Santos CF, Silva AP, Lopes L, et al. Design and production of sintered β-tricalcium phosphate 3D scaffolds for bone tissue regeneration. Ma- terials Science and Engineering C, 2012, 32(5): 1293-1298.
  • 6Martinez-Vazquez FJ, Perera FH, Miranda P, et al. Improving the compressive strength of bioceramic robocast scaffolds by polymer infiltration. Acta Biomater, 2010, 6( 11): 4361-4368.
  • 7Xiang Li, Dichen Li, Bingheng Lu, et al. Fabrication of bioceramic scaf- folds with pre-designed internal architecture by gel casting and indirect stereolithography techniques. J Porous Mater, 2008, 15: 667-671.
  • 8Li X, Bian W, Li D, et al. Fabrication of porous beta-tricalcium phos- phate with microchannel and customized geometry based on gel- casting and rapid prototyping. Proc Inst Mech Eng H, 2011, 225(3): 315-323.
  • 9Miranda P, Pajares A, Saiz E, et al. Fracture modes under uniaxial compression in hydroxyapatite scaffolds fabricated by robocasting. J Biomed Mater Res A, 2007, 83(3): 646-655.
  • 10Miranda P, Pajares A, Guiberteau F. Finite element modeling as a tool for predicting the fracture behavior of robocast scaffolds. Acta Bioma- ter, 2008, 4(6):1715-1724.

引证文献9

二级引证文献49

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部