慈姑多糖降血糖的生物活性研究

Research on Hypoglycemic Effect of the Sagittaria Sagittifolin Polysaccharide

目的:考察慈姑多糖对四氧嘧啶性糖尿病模型小鼠血糖的影响。方法:采用皮下一次性注射190 mg/kg四氧嘧啶致实验性糖尿病小鼠,观察慈姑多糖不同剂量(0.75 g/kg,0.375 g/kg)对糖尿病小鼠空腹血糖的影响。结果:慈姑多糖高、低剂量组能显著性降低血糖水平(P<0.05)。结论:慈姑多糖具有一定的降血糖作用。

Objective： To observe the hypoglycemic effect of polysaccharide from Sagittaria sagittifolin in alloxan-induced diabetic mice. Methods： The diabetic model mice were established by intra-abdominal injection of 190 mg/kg alloxan, the hypoglycemic effects of Sagittaria sagittifolin polysaccharide in 0.75 g/kg and 0.375 g/kg were examined. Results： Sagittaria sagittifohn polysaccharide in two doses could both significantly decrease the blood glucose in diabetic mice （P〈0.05）. Conclusion： Sagittaria sa,,ittifolin Dolvsaccharide showed certain hypoglycemic effect on diabetic mice model.