24例角膜内皮炎综合症患者临床观察

Clinical Observation of 24 Patients with Corneal Endotheliitis Syndrome

目的:探讨角膜内皮炎的病因、诊断、抗病毒药物及皮质类固醇激素治疗的临床疗效。方法:对24例角膜内皮炎患者临床特点及治疗效果进行回顾性分析。结果:24例患者均获治愈,随访6月～1年,复发3例,所有病例视力均有不同程度提高,经治疗后:视力达0.1～0.3者3例,0.3～0.5者12例,0.6～0.8者5例,>0.8者4例,5例遗留角膜瘢翳,11例遗留角膜云翳。结论:角膜内皮炎强调早期诊断、及时给予病因治疗,局部或全身应用抗病毒药物联合皮质类固醇激素治疗可有效缓解病情,减少复发率。

J Objective： To explore the etiology, diagnosis as well as the antiviral drugs and cortlcosterold holmone treatment ot corneal endotheliitis. Methods： Clinical characteristics and treatment effectiveness of 24 cases of patients with the corneal endotheliitis were conducted retrospective anlysis. Results： All patients with the corneal endotheliitis were cured. Three cases of corneal inflammation recurred during the following-up of 6-12 months. After the etiological treatment was performed, visual acuity improved among 24 patients： 3 patients with 0.1-0.3 visual acuity improvement, 11 patients with 0.3-0.5, 5 patients with 0.6-0.8 and 3 patients with more than 0.8 improvment. Corneal macula were observed in 5 cases and l 1 cases of corneal nebula. Conclusion： The early diagnosis and therapy was emphasized on the corneal endotheliitis, local or systemic application of antiviral drugs combined with eortieosteroid hormone could effectively alleviate the symptom, and reduce the relapse rate.