减少不良右室起搏的临床研究

Clinical research of reducing ventricular pacing with the managed ventricular pacing mode

目的观察心室起搏管理(Managing Ventricular Pacing,MVP)功能减少心室起搏百分比的效果。方法选择因病态窦房结综合征或房室阻滞而植入具有MVP功能的美敦力Adapta系列起搏器的患者共50例,分别程控为DDD模式和MVP模式,3个月后交叉程控为MVP模式和DDD模式,再随访3个月。结果两组患者DDD模式期间心室起搏百分比分别为40.5%(1.3%～90.1%)和39.9%(1.0～91.6%),两组患者MVP模式期间心室起搏百分比分别为5.8%(0～40.2%)和6.4%(0～32.4%)。MVP模式期间的心室起搏百分比明显低于DDD模式期间(p<0.05)。结论 MVP起搏模式能够降低因病态窦房结综合征或房室阻滞行永久性双腔人工心脏起搏器治疗患者的心室起搏百分比。

Objective To investigate the effect of reducing ventricular pacing with the managed ventricular pacing（MVP） mode. Methods The Medtronic Adapta cardiac pacemakers were implanted in 50 patients with sick sinus syndrome or atrial-ventricular block. Patients were randomized to the DDD mode or MVP mode for three months, then crossed over to the alternate pacing modality for an additional three months. Results The cumulative percent of ventricular pacing was significantly reduced in the MVP mode [40.5%（1.3%～90.1%） and 39.9%（1.0%～91.6%）] compared to the DDD mode [5.8%（0%～40.2%） and 6.4%（0%～32.4%）]（p0.05）. Conclusion The MVP mode reduces the amount of right ventricular pacing in patients with sick sinus syndrome or atrial-ventricular block.