医院获得性肺炎148例危险因素分析

Risk Factors Analysis of 148 cases of Hospital cquired pneumonia

目的探讨医院获得性肺炎(HAP)发生的危险因素。方法分析本院确诊医院获得性肺炎的患者148例作观察组,与同期未发生医院获得性肺炎的148例患者作对照组。结果两组患者年龄>65岁,入住ICU、留置导尿>3 d、留置胃管>2 d、插管机械通气、联合应用2种以上抗生素、应用抑酸药物、存在基础疾病,这些情况间差别均有显著性意义(P<0.05),其中年龄>65岁、联合应用2种以上抗生素、入住ICU、留置胃管>2 d、插管机械通气、应用抑酸药物、存在基础疾病是医院获得性肺炎的独立危险因素。结论医院获得性肺炎发生是多因素共同作用的结果,必须针对重点人群、高危因素及相关环节进行防治。

Objective To explore hospital-acquired pneumonia （HAP） risk factors. Methods A retrospective analysis of our hospital in January 2007-July 2011 diagnosis of hospital-acquired pneumonia in 148 patients for the study group, did not occur with the same period of hospital-acquired pneumonia in 148 patients as the control group, univariate and multivariate logistic regression analysis. Results There were age 〉65 years old, stay ICU, catheterization 〉 3d, indwelling stomach tube 〉 2d, intubation, mechanical ventila- tion, combined with more than two kinds of antibiotics, the application of acid-suppressing drugs, there is underlying disease, the differ- ence between these cases are there were significant （ P 〈 0. 05 ）, in which age 〉 65 years, the combination of 2 or more antibiotics, stay 1CU, indwelling stomach tube 〉2d, intubation, mechanical ventilation, the application of acid-suppressing drugs, there is a hospital-acquired disease is based independent risk factor for pneumonia. Conclusion hospital-acquired pneumonia is the result of many factors must be for the focus groups, risk factors and related aspects of prevention and treatment.