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定向抗菌预防法在防治经直肠前列腺穿刺活检术后感染的应用价值 被引量:4

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摘要 目的探讨定向抗菌预防法在防治经直肠前列腺穿刺活检术后感染的应用价值。方法将本院2008年7月~2012年4月行经直肠B超引导下前列腺穿刺活检的344例患者随机分成3组:A组常规术前稀碘伏灌肠组105例;B组:术前稀碘伏灌肠联合经验性使用环丙沙星组117例;C组术前稀碘伏灌肠联合根据肛拭子培养结果定向抗菌预防组122例。穿刺后观测患者体温变化,血尿培养结果,按标准认定感染。结果 A组105例中17例发热,3例出现前列腺脓肿,1例出现败血症;B组117例中3例出现发热,1例出现菌血症,1例出现前列腺炎,无前列腺脓肿及菌血症患者出现;C组全部122例病例中无1例出现术后发热、前列腺炎、脓肿及败血症等临床感染。结论前列腺穿刺活检前后预防性抗生素可减少前列腺穿刺引起尿路感染;虽然环丙沙星可提供很好的感染预防效果,但定向抗菌预防法更可显著减少患者术后感染并发症发病率及患者抗生素使用率。
出处 《现代泌尿外科杂志》 CAS 2013年第1期78-79,共2页 Journal of Modern Urology
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