重视干眼的炎症反应研究及防治

Emphasizing the prevention and anti.inflammation research of dry eye disease

干眼是眼科常见的眼表疾病。一般治疗只注重泪液成分的补充，而对炎症反应在干眼发病过程中的作用重视不够。随着干眼定义的修订及干眼中炎症反应研究的深入，炎症反应和干眼相伴相随的关系不容忽视，干眼抗炎治疗中糖皮质激素应用应当谨慎，环孢素A和非甾体类滴眼剂值得关注。我国应重视多中心干眼炎症反应及流行病学研究，规范干眼的综合治疗。

Dry eye disease is a common ocular surface disorder among ophthalmological conditions. Treatment generally focuses on tear supplement by topical artificial tears but less focus on the immunological changes in the pathogenesis of the dry eye. As our understanding of the pathology of the disease improves, new definitions are being developed. It turns out that inflammation, and dry eye accompanied relationship can not be ignored. Topical corticosteroid therapy for dry eye should be more cautioned and topical use of Cyclosporin A （CsA） and nonsteroidal anti-inflammatory drugs （NSAIDs） require more attention. In order to standardize management strategies for dry eye, multi-center studies for the link between inflammation and dry eye are needed, and epidemiological survey should be performed.