肺郎格罕氏细胞组织细胞增生症的CT表现

CT findings of pulmonary langerhans' cell histiocytosis in adults

目的探讨肺朗格罕氏细胞组织细胞增生症(PLCH)的CT表现及鉴别诊断,提高对该疾病的认识。方法回顾性分析6例经病理证实的肺郎格罕细胞组织细胞增生症患者的临床和CT资料,分析病变的形态、数目、大小及分布情况。结果 2例早期PLCH,CT表现为双肺以中上肺野为主广泛分布的小片状、结节状病灶;2例中期PLCH,CT表现为两肺弥漫性小结节伴囊状透亮影;2例为晚期PLCH,CT表现为双肺以中肺野为主广泛分布的大小不等的圆形、类圆形低密度透光区伴纤维条索影,部分呈囊状和蜂窝状病灶,其中1例并合并反复气胸。结论 PLCH的CT表现有一定特征性,各期病灶可相互存在,早期诊断对PLCH的治疗起关键的作用。

Objective To study the CT findings and differentical diagnosis of each stage pulmonary langerhans＇ cell histiocytosisand in adults, and to make a further understanding of the disease. Methods Six patients＇CT and clinical data with pathologically confirmed PLCH were retrospectively analyzed, including the morphology, number and distribution of the leision. Results CT manifestations of two cases with early PLCH were multiple small flake, nodular lesions, which were widly distributed mainly in the upper and middle lung field; two cases with interim PLCH were diffused small nodules with cystic translucent shadow; two cases of late PLCH were widely distributed sizes of round oval low density photic zone associated with the fibers of the cable video mainly in the middle lung field, partly were cystic and honeycomb lesions, including one case with repeated pneumothorax. Conclusion PLCH has special changes in CT findings, each stage of lei sions can coexist, and the early diagnosis of PLCH plays a key role for treatment.