原发性胆汁性肝硬化临床诊断及治疗研究

Clinical diagnosis and treatment of primary biliary cirrhosis

目的探讨原发性胆汁性肝硬化的临床诊断及治疗。方法选取笔者所在医院2007年4月～2010年9月收治的78例原发性胆汁性肝硬化患者,将78例患者随机分为两组,观察组40例,对照组38例,观察组给予异甘草酸镁静脉滴注,熊去氧胆酸胶囊治疗,对照组仅给予熊去氧胆酸治疗,同时记录所得数据。结果观察组40例患者中,显效19例,有效15例,无效6例,治疗有效率为85.0%,对照组38例患者中,显效15例,有效14例,无效9例,治疗有效率为76.3%。结论采用异甘草酸镁联合熊去氧胆酸胶囊治疗原发性胆汁性肝硬化疾病的效果显著,值得在临床推广应用。

Objective To explore the clinical diagnosis and treatment of primary biliary cirrhosis. Methods Selecting 78 cases of primary hiliary cirrhosis patients from my courtyard in April 2007 to September 2010, and 78 patients were randomly divided into two groups, 40 cases in the observation group,38 cases in the control group,the observation group was given magnesium isoglycyrrhizinate in intravenous infusion,ursodeo- xycholic acid capsules in the treatment,the control group was only given the ursodeoxycholic acid treatment, and then recorded the data. Results The efficiency rate of 40 patients of the observation group was 85.0%, and the efficiency rate of 38 patients of the control group was 76.3%.Conclusion Using magnesium isoglycy-rrhizinate combined with ursodeoxycholic acid capsules in the treatment of primary biliary cirrhosis of liver diseases has significant effect, and the treatment. The method is worth to use in the clinical application.