多层螺旋CT低剂量扫描在监测早期肺癌动态进展的应用价值研究

The value of low-dose multislice spiral CT scanning in monitoring the dynamic progress of early stage lung cancer

目的探讨多层螺旋CT低剂量扫描在监测早期肺癌动态进展的应用价值。方法选择早期肺癌患者295例,分析其普通CT及低剂量CT图像特点,于初次检查后每3月复查CT进行密切随访,观察病灶的变化情况。结果①在直径<5mm、5～10mm及>10mm的早期肺癌的诊断及对肺癌CT征象的显示中,普通CT扫描与低剂量CT扫描间差异无统计学意义(P>0.05)。②随访过程中,31例病灶无明显变化,90例病灶径线变大,表现为软组织肿块体积增大,边缘毛刺更加明显,出现胸膜凹陷征、血管集束征及分叶征。其中12例病灶出现转移,包括肺内播散及远处转移。结论在早期肺癌的诊断和随访观察中,多层螺旋CT低剂量扫描具有较高的应用价值。

Objective To investigate the value of multislice CT low dose scanning dynamic progress in the monitoring of early stage lung cancer. Methods 295 cases of early stage lung cancer patients were chosen, conventional CT and low-dose CT image characteristics, and follow-up CT scan every three months after the initial inspection were analyzed. Results （1）In lung cancers with diameter less than 5 mm,5-10 mm and greater than 10 mm in the early diagnosis,lung cancer CT iamges showed no significant difference between the conventional CT scanning and low-dose CT scan（P〉0.05）. （2）During follow-up,31 cases of lesions showed no significant change and 90 cases with the lesion diameter enlarged, with increases in soft tissue mass, volume, edge burr more evident, there pleural indentation and vascular convergence sign and lobulation. The transfer of 12 cases of lesions, including the lungs spread and distant metastasis. Conclusion in the early lung cancer diagnosis and follow-up observations, multi-slice spiral CT with low dose scanning has high value.