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miRNA在心血管疾病中的研究进展 被引量：6

The Progression of miRNAs in Cardiovascular disease
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摘要 MicroRNAs（miRNAs）是一类长度为21~25个核糖核苷酸的非编码内源性小单链RNAs分子,在转录后水平调控蛋白质的表达,几乎参与所有生命体的生理和病理过程。最近研究显示miRNAs在心血管系统发生及病理生理方面发挥至关重要作用。循环miRNAs概念的引入,使得对其研究变得更加方便,可能作为新的心血管疾病生物标志物。本文就miRNA在心血管方面的研究进展加以综述。 MicroRNAs （miRNAs） are a class of 21 to 25 non-coding endogenous ribonucleotide small single-stranded RNAs, that regulate protein expression in the post-transcriptional level, and participate in almost all life physiological and pathological processes. Recent studies have shown that miRNAs play an important role in the development and pathophysiology in cardiovascular system. It is convenient to study as the intro- duction of circulating miRNAs, and can be used as new biomarkers for cardiovascular disease. Now we make a review of miRNAs in cardiovascular system.
作者 王玺 邱春光 黄振文
机构地区 郑州大学第一附属医院心内科
出处 《中国分子心脏病学杂志》 CAS 2012年第6期375-379,共5页 Molecular Cardiology of China
关键词 MIRNAS 心血管疾病 标志物 miRNAs Cardiovascular disease Biomarker
分类号 R54 [医药卫生—心血管疾病]
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同被引文献69

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引证文献6

二级引证文献23

中国分子心脏病学杂志
2012年 第6期

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