银丹心脑通软胶囊治疗慢性稳定型心绞痛临床观察

Clinical observation of “Yindan Xinnaotong Capsule” in treating chronic stable angina pectoris

目的观察银丹心脑通软胶囊治疗慢性稳定型心绞痛的临床疗效。方法将100例慢性稳定型心绞痛患者随机分为两组;除给予抗血小板、调脂等基础治疗外,治疗组50例另予银丹心脑通软胶囊口服,对照组50例另予复方丹参片口服。两组疗程均为4周,观察心绞痛发作频率和持续时间、硝酸甘油用量、血脂变化情况,并评价心绞痛疗效、心电图疗效,观察不良反应发生情况。结果治疗组、对照组心绞痛总有效率分别为82.0%、52.0%;组间心绞痛疗效比较,差异有统计学意义(P<0.05)。治疗组、对照组心电图总有效率分别为52.0%、30.0%;组间心电图疗效比较,差异有统计学意义(P<0.05)。治疗组在减少心绞痛发作次数、持续时间、硝酸甘油用量等方面亦优于对照组(P<0.05)。结论银丹心脑通软胶囊治疗慢性稳定型心绞痛疗效显著。

Objective To observe the clinical effect of ＂Yindan Xinnaotong Capsule＂ in the treatment of chronic stable angina pectoris. Methods One hundred subjects were equally randomized into treatment group and control group; the two groups were given routine western medicine ; in addition, the treatment group was given ＂Yindan Xinnaotong Capsule＂ and the control group was given ＂Fufang Danshen Tablet＂, with a course of 4 weeks. The onset frequency, duration of angina pectoris, dosage of nitroglycerin, blood lipids, electrocardiogram and adverse reactions were observed. Results The total effective rate for angina pectoris was 82.0% in the treatment group and 52.0% in the control group, with a difference between the two groups（ P 〈 0.05 ） ; the total effective rate for electrocardiogram was 52.0% in the treatment group and 30.0% in the control group, with a difference between the two groups（P 〈 0.05 ）. The onset frequency, duration of angina pectoris and dosage of nitroglycerin were improved more significantly in the treatment group than in the control group （ P 〈 0.05 ）. Conclusion ＂Yindan Xinnaotong Capsule＂ is quite effective for chronic stable angina pectoris.