甲亢危象患者脂质代谢的特点分析

目的分析甲亢危象患者的脂质代谢特点。方法回顾性分析收治的51例甲亢危象患者血脂各指标水平,并与60例体检正常者组成的对照组血脂各指标水平对比;同时分析甲亢危象患者TG、TC、HDL-C及LDL-C与FT3、FT4的相关性。结果甲亢危象组患者TG、TC、HDL-C及LDL-C均显著低于对照组(P<0.05);TG、TC与FT3呈负相关(r=-0.569,P<0.01;r=-0.473,P<0.01),TC与FT4呈负相关(r=-0.726,P<0.01)。结论甲亢危象患者存在严重脂代谢紊乱且与甲状腺激素特别是FT3水平显著相关,临床救治当中应予以重视。

Objective To research the characteristics of lipid metabolism of patients with thyroid crisis. Methods Chose 51 patients with thyroid crisis as observation group, and chose 60 healthy people as control group. Plasma TG, TC, HDL-C and LDL-C of all testers were simultaneously detected. Compare the levels of the 2 groups and analyse the relativity of lipid level with FT3 and FT4. Results The levels of plasma TG, TC, HDL-C and LDL-C of thyrotoxic crisis were all significantly lower than control group （P〈0.01）. levels of TG and TC were negatively correlated with FT3 （r=-0.569, P〈0.01; r=-0.473, P〈0.01） while level of TC was negatively correlated with FT4 （r=-0.726, P〈0.01）. Conclusion Lipid metabolism disorders occur in patients with thyroid crisis, which should be paid more attention to in clinical treatment.