354例新生儿高胆红素血症血小板参数分析

目的探讨高胆红素血症新生儿血小板参数和白细胞变化与黄疸程度的关系。方法对354例高胆红素血症新生儿和36例正常新生儿采用全自动血细胞分析仪测定血小板计数(PLT)、血小板体积(MPV)、血小板分布宽度(PDW)、白细胞计数(WBC),按黄疸程度分为轻度、中度、重度3组比较。结果各组间PLT、MPV、WBC均值比较均无显著性差异(P值均>0.05)。中度高胆组PDW与正常对照组和重度高胆组比较,差异有统计学意义(P值均<0.05)。结论高胆与血小板参数和WBC的变化没有明显关系。

Objective To investigate the relation between the changes ofplatelet parameters and white blood cells and the degree of jaundice. Methods The platelet parameters 0aLT）, the platelet volume （MPV）, the platelet distribution width （PDW） and the peripheral blood leukocytes （WBC） were detected by automatic blood cell analyzer respectively in 354 cases of neonatal hyperbilirubinemia and 36 normal neonates. The neonates were divided into three groups as the light degree, the moderate degree and the severe degree according to the degree of jaundice. Results The averages of PLT, MPV and WBC among the groups were compared. It showed that there was no significant difference （P〉0.05）. The PDW of the moderate degree group with the normal group and the severe degree group were compared, the difference had statistical significance （P〈0.05）. Conclusion There is no patent relation between the hyperbilirubinemia and the platelet parameters as well as the changes of WBC.