早期全静脉营养对低体重儿营养状态及生化指标的影响

Influence of early total parenteral nutrition on nutrition state and biochemical indexes of low-birth-weight infants

目的:探讨早期全静脉营养对低体重儿营养状态及生化指标的影响。方法:选取2009年5月～2012年9月于本院进行早期全静脉营养干预的32例低体重儿为观察组,同期进行传统静脉营养干预的32例低体重儿为对照组,将两组小儿干预前及干预后不同时间段的生长发育、营养状态及生化指标进行比较。结果:观察组干预后不同时间段的生长发育指标均大于对照组,血清前白蛋白高于对照组,尿素氮、胆红素及肌酐均低于对照组,红细胞免疫指标及微量元素改善幅度均大于对照组,差异有统计学意义(P均<0.05)。结论:早期全静脉营养可有效改善低体重儿的营养状态及生化指标,可有效改善低体重新生儿的综合状态。

Objective; To study the influence of early total parenteral nutrition on nutrition state and biochemical indexes of low-birth-weight infants. Methods：A total of 32 low-birth-weight infants who were treated with early total parenteral nutrition in our hospital from May 2009 to September 2012 were selected as observation group,32 low-birth-weight infants who were treated with traditional parenteral nu- trition at the same time were selected as control group, then the growth,nutrition state and biochemical in- dexes of two groups before and after the intervention at different times were compared. Results： The growth indexes of observation group after the intervention at different times were all higher than those of control groups the serum prealbumin were higher than those of control group~ blood urea nitrogen, biliru- bin and creatinine were all lower than those of control group~ the improvement range of erythrocyte im- mune indexes and trace elements were all better than those of control group （P〈0.05）. Conclusions. Earlytotal parenteral nutrition can effectively improve the nutrition state and biochemical indexes of low-birth- weight infants, and it can effectively improve the comprehensive sate of low-birth-weight infants.