糙米皮对高脂血症大鼠血脂水平的影响

Effects of Rice Outer Layer Fraction on Serum Lipid of Hyperlipemia Rats

研究功能稻良种"福紫681"和"福红819"的米皮对高脂血症大鼠血脂的调节作用。健康雄性SD大鼠50只,应用高脂饲料喂养方法建立高脂血症动物模型,黑米皮和红米皮灌胃治疗56 d,取血处死动物,取肝脏和脂肪。生化法检测大鼠血清TG、TC、LDL-C、和HDL-C水平。结果:经黑米皮和红米皮干预治疗后,与模型组相比较,大鼠体质量增幅分别降低了33.16%和39.40%,肝指数分别降低了12.26%和16.89%,脂肪指数分别降低了35.71%和20.86%。黑米皮组动物血清TC、TG和AI较模型组分别降低了17.82%、57.33%和39.81%,而HDL-C水平提高了24.24%。红米皮组HDL-C水平提高48.48%,AI降低29.21%。黑米皮和红米皮不同程度影响高脂血症大鼠血清TG、TC、LDL-C和HDL-C水平,对实验性高血脂的形成具有一定的预防控制效应。

The regulating effects of functional rice ＂Fuzi 681＂ and ＂Fuhong 819＂ outer layer fraction on serum lipid of hyperlipemia in rats were investigated via establishing hyperlipemia models by feeding fat-rich forage to fifty healthy make SD rats, i.g. administer black and red rice outer layer fraction for 56d, and collecting blood, tissue and fats sample for analysis. Using bio-chemical method, the levels of the levels of serum lipid were tested including the triglyceride （TG）, total cholesterol （TC）, low-density lipoprotein （LDL）, high-density lipoprotein （HDL） Results showed that after treated with black and red rice outer layer fraction, the increase rate of rats body weight decreased 33.16% and 39.40%, respectively, and liver index decreased 12.26% and 16.89%,respectively. The fat index decreased 35.71% and 20.86%, respectively.The black rice group levels of serum TC~ TC andAI decreased 17.82%, 57.33% and 39.81%, respectively and the serum HDL increased 24.24% compared to those in model group rats （P〈0.05）. The red group the levels of serum AI decreased 48.48% and the serum HDL increased 29.21% compared to those in model group rats. Black and red rice outer layer fraction effect differently on hyperlipemia rats serum TC~ TC, LDL-C and HDL-C levels,being effective in preventing the formation of hyperlipidemia of the experimental rat.