MP、CP与哮喘预测指数阳性小儿发病相关性研究

Study on correlation between mycoplasma pneumonia （MP）, chlamydia pneumoniae （CP） and asthma index as apredictor ~ positive

目的探讨肺炎支原体（MP）、肺炎衣原体（cP）与哮喘预测指数阳性小儿喘息发作的关系。方法对2009年1月至2011年12月我科收治的患喘息性呼吸道疾病（包括痉挛性支气管炎、喘息型肺炎）的婴幼儿120例，根据预测指数将患几分为预测指数阳性组62例和预测指数阴性组58例，检测两组患儿血清MP-IgM、CP-IgM，并进行组问比较。结果预测指数阳性组中，MP-IgM阳性15例，CP-IgM阳性18例；预测指数阴性组中，MP-IgM阳性5例，CP-IgM阳性7例。结论MP、CP与哮喘预测指数阳性小儿喘息发作有关，应及时完善相关特异性抗体检测，予大环内酯类药物合理治疗以控制急性喘息发作、减少学龄期儿童哮喘的发病率。

Objective To explore the correlation between mycoplasma pneumonia （MP）, chlamydia pneu- moniae （CP） and asthma index as a predictor of positive. Methods We separated 120 received infants who suf- fered from the asthmatic respiratory disease （included the bronchitis convulsive and asthmatic pneumonia）. We separated the infants into experimental group i.e. predictive index for positive group （62 infants） and control group i.e. predictive index of negative group （58 infants）, and we checked the MP-IgM, CP-IgM of the two groups of in- fants and compared the groups. Reaulta 15 infants of the experimental group had the positive MP-IgM and the positive rate was 24.2%. 18 infants of the experimental group had the positive CP-IgM and the positive rate was 29%. And the relative positive rate of the control group was 8.6% and 12.1%. The discrepancy of two group had statistical significant difference （P〈0.05）. Conclusion MP, CP have some relation with the asthma index as a pre- dictor of positive. We need to improve the related specific antibody detection, and to macrolides in treatment of a- cute asthmatic attack in order to decrease incidence of asthma disease in school age children.