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吡柔比星联合多西它赛紫杉醇治疗妇科恶性肿瘤方面的临床研究 被引量:3

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摘要 目的观察紫杉醇联合THP(吡柔比星)治疗晚期宫颈癌的临床疗效以及毒性反应。方法自2009年8月至2011年5月来我院的患有晚期宫颈癌的45例患者,对其采用吡柔比星40mg/m^2,静脉注射,dl;采用多西它赛紫杉醇135mg/m^2,静脉滴注3h,dl。以21天为1个周期,连续使用2个周期以上,然后评价疗效。结果45例患者中,CR7例05.56%),PR25例(55.56%),SD11例(24.44%),PD2例(4.44%1,总有效率为71.11%(32/45)。不良反应主要在骨髓抑制方面及脱发。结论吡柔比星联合多西它赛紫杉醇治疗晚期恶性宫颈癌疗效较好,不良反应轻,可耐受,是一种有效、安全的方法,适合在临床推广应用。
出处 《国际医药卫生导报》 2013年第2期196-197,共2页 International Medicine and Health Guidance News
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