摘要
报道了聚乙二醇(MeO-PEG)负载的二茂铁噁唑啉衍生的手性N,P和N,S配体的合成.所得负载N,P配体可以成功应用于银催化的[3+2]环加成反应,最高取得了97%的对映选择性.另外聚乙二醇负载二茂铁N,S配体可以成功应用于钯催化的烯丙基取代反应,取得了90%的ee值.值得注意是,聚乙二醇负载形成的催化剂循环使用4次后其催化活性和选择性仍可基本保持.
A simple synthesis of ferrocenyloxazoline derived chiral N,P ligands and N,S ligands immobilized on a MeO- PEG-support is described. The metal complexes of chiral ligands have been successfully applied to 1,3-dipolar cycloaddition reaction of azomethine ylides and asymmetric allylic substitution reaction, providing the products with up to 97% ee and 90% ee, respectively. The MeO-PEG-supported metal complex catalysts can be recycled easily and reused.
出处
《化学学报》
SCIE
CAS
CSCD
北大核心
2013年第1期40-43,共4页
Acta Chimica Sinica
基金
Project supported by the National Natural Science Foundation of China(Nos.21202162&21125208)
the National Basic Research Program of China(No.2010CB833300)~~
