沙丁胺醇雾化吸入联合黄芪注射液治疗COPD的临床观察

Clinical Observation of Aerosol Inhalation of Salbutamol Combined with Huangqi Injection in the Treatment of Chronic Obstructive Pulmonary Disease

目的:观察沙丁胺醇雾化吸入联合黄芪注射液治疗慢性阻塞性肺疾病(COPD)的疗效。方法:回顾分析我院2009年10月-2012年6月93例COPD患者的临床资料,其中对照组45例,在常规治疗基础上给予沙丁胺醇雾化吸入治疗;治疗组48例,在常规治疗基础上给予沙丁胺醇雾化吸入联合黄芪注射液静脉滴注,比较2组患者治疗前后的呼吸困难评分、肺功能和血气分析情况,以评价2组患者的疗效。结果:治疗后,2组患者临床症状均有所改善,治疗组呼吸困难、肺功能和血气分析改善程度均显著高于对照组(P<0.05)。治疗中,2组均有部分患者有轻微不良反应,但不影响继续治疗。结论:沙丁胺醇雾化吸入联合黄芪注射液治疗COPD效果良好,疗效优于单用沙丁胺醇雾化吸入。

OBJECTIVE：To observe the efficacy of aerosol inhalation of salbutamol combined with Huangqi injection in the treatment of chronic obstructive pulmonary disease（COPD）.METHODS：The clinical data of 93 patients with COPD between Oct.2009 and Jun.2012 were analyzed retrospectively.Among them,45 cases of control group were treated with aerosol inhalation of salbutamol on the basis of conventional treatment,and 48 cases of treatment group were treated with aerosol inhalation of salbutamol combined with intravenous drip of Huangqi injection.The dyspnea score,lung function and blood gas analysis were compared between 2 groups before and after treatment,and therapeutic efficacies were evaluated in 2 groups.RESULTS：The clinical symptoms of patients in 2 groups were improved.The improvement of dyspnea,blood gas analysis and lung function in treatment group were significantly higher than in control group（P0.05）.Slight ADR was found in some patients in 2 groups,which didn＇t affect continuous treatment.CONCLUSION：Aerosol inhalation of salbutamol combined with Huangqi injection is effective for COPD,and its efficacy is better than that of salbutamol alone.