血清及胸水铁蛋白测定在呼吸系疾病中的初步应用

DETERMINATION OF SF AND TF IN RESPIRATORY DISEASES

本文测定健康成人血清铁蛋白。男性,女性分别为93.7及64.0μg/L,60岁以上老年为103.14μg/L。肺炎、结核、肺癌患者血清铁蛋白男性、女性间无明显差异,但分别高于同性别正常组,也均高于正常老年组;尤其肺癌组明显高于其他各组。同一患者胸水铁蛋白高于血清铁蛋白。肺癌胸水铁蛋白最高。血清及胸水铁蛋白测定可作为炎症、结核、肺癌诊断方法之一。

Serum ferritin (SF) was determined in 113 healthy adults, including 53 males and 60 females, with a mean value of 93.7 and 64.0 μg/L respectively. The difference was of statistical significance(P<0.01).SF also increased with aging, and in old healthy people it was 103.4 μg/L in average.In patients with pneumonia, pulmonary tuberculosis, and lung cancer, there was no significant difference between males and females.However, the SF levels in the diseased groups were higher than those in the normal controls of the same sex,including the old patients and the healthy old controls(P<0. 01).It was highest in patients with lung cancer, especially undifferentiated lung cancer. The content of ferri-tin in the pleuritic fluid(TF)was higher than that of SF in the same patient, and TF in patient with lung cancer was the highest. SF and TF may be used in differential diagnosis for pneumonia, TB and lung cancer.Marked elevation of SF may be used as the basis for early diagnosis in lung cancer inparticular.