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雄激素受体在乳腺癌中的表达及临床意义 被引量:5

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摘要 目的研究雄激素受体(AR)在乳腺癌组织中的表达及临床意义。方法用免疫组化法检测AR在乳腺癌组织中的表达,并结合临床、病理资料进行分析。结果乳腺癌组织中的AR表达与肿瘤大小呈负相关(r=-0.403,P<0.05),与年龄、是否绝经、病理学类型、有无脉管瘤栓、淋巴结转移无相关性(P>0.05),与组织学分级呈负相关(r=-0.447,P<0.05),与ER、PR、Her-2、Ki-67的无相关性(P>0.05)。结论 AR与乳腺癌有相关性,可以作为一个判断预后的指标及指导内分泌治疗的参考。
作者 张文进
出处 《河北医药》 CAS 2013年第2期187-188,共2页 Hebei Medical Journal
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参考文献11

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