降解胆固醇乳酸菌的筛选及中草药与乳酸菌的协同作用(英文)

Screening of Cholesterol-Lowering Lactic Acid Bacteria and Synergic Effect with Chinese Herbal Medicines

从酸菜与酸奶中筛选具有降解胆固醇功能的乳酸菌。通过对低pH值耐受性、胆盐耐受性、拮抗条件致病微生物的特性,研究其潜在的益生功能。结果显示,筛选到8株降解胆固醇的乳酸菌,LAB4菌株具有较好的耐受胆盐与低pH值的特性,8株菌株对金黄色葡萄球菌和大肠埃希氏菌均有拮抗作用。同时研究了LAB4菌株与中草药协同降解胆固醇的作用,结果表明,0.0125%的甘草、0.025%的枸杞或黄芪与LAB4菌株具有协同降解胆固醇的功能。

Eight cholesterol-lowering lactic acid bacteria （LAB 1 through 8） isolated from pickles and yogurt were evaluated for probiotic potential based on their tolerance to low pH and bile salt and antagonistic activity against Staphylococcus aureus and Escherichia coli. Strain LAB 4 had excellent tolerance to low pH and bile salt and all 8 LAB strains had antagonistic activity against Staphylococcus aureus and Escherichia coli. Moreover, strain LAB 4 had synergic cholesterol-lowering effect with 0.0125% licorice root extract, 0.025% Chinese wolfberry extract or 0.025% milkvetch root extract.