水产低值鱼抗菌肽研究进展

Research Progress of Antimicrobial Peptides from Aquatic Low-value Fish

抗菌肽是生物防御系统产生的一类对抗外源性病原体的肽类物质,具有抗细菌、真菌、病毒、原虫、癌细胞等多种活性,目前发现抗菌肽或类似抗菌肽的小分子肽类广泛存在于昆虫、两栖类、水产动物及哺乳动物中,具有广阔的应用前景。现就抗菌肽的理化特征、结构特点、应用前景等几个方面系统地阐述水产低值鱼抗菌肽的研究进展。

Antimicrobial peptides are antiexogenous pathogens peptides produced by biological defense system ,with various activities such asantibacterial, antifungal, antimould, antivirus, anti-protozoon, and anti- cancer cells, etc.. Studies found that antimicrobial peptides, which have wide application prospects, exist widely in insects, amphibians, aquatic animals and mammals. Here is to make a review on the research pro- gress of the physical and chemical characteristics, the structure characteristics, the application prospect of an- timicrobial peptides in aquatic low-value fish.