小儿肺炎支原体感染诊治研究进展

Research Progress in Diagnosis and Treatment of Childhood Mycoplasma Pneumoniae Infections

肺炎支原体(MP)是小儿社区获得性肺炎常见的病原体之一,MP感染既有呼吸道症状,又可导致肺外多系统损害,血清特异性抗体检测依然是目前临床诊断MP感染的主要手段,聚合酶链反应技术可用于MP感染的早期诊断。大环内酯类仍是治疗小儿MP感染的首选抗生素,糖皮质激素及免疫球蛋白可用于重症MP感染,MP肺炎合并肺不张应争取在病程早期行纤维支气管镜灌洗治疗。

Mycoplasma pneumoniae （MP）in children is one of the common pathogens in community-ac- quired pneumonia. MP infection has both respiratory symptoms and extrapulmonary multi-system damages. Se- rum specific antibodies is still the primary means of clinical diagnosis of MP infection. Polymerase chain reac- tion（PCR） technology cart be used for earlier diagnosis of MP infection. Macrolides is still the main antibiotic for the treatment. Corticosteroid and immunoglobulin can be used for intensive MP infection. MP pneumonia complicated with atelectasis should be treated flexible bronchoscopy lavage in the early stage of the disease as soon as possible.