内镜逆行胰胆管造影术后胰腺炎的防治进展

Progress in Prevention and Treatment of Post-ERCP Pancreatitis

经内镜逆行胰胆管造影术(ERCP)是肝胆胰疾病重要的诊治手段,尤其是治疗性ERCP在肝胆胰疾病的微创治疗中占有越来越重要的地位,已越来越多地应用于临床。因ERCP是有创技术,难免出现一些并发症,ERCP术后胰腺炎是常见的并发症,发生率较高,其发生主要与胰管显影、插管困难等诸多因素有关。虽然ERCP术后胰腺炎的防治方法很多,如术前预防用药、术中放置胰管支架、鼻胆管引流等,但ERCP术后胰腺炎的发生仍是困扰临床医师的一大难题,随着ERCP诊治技术的广泛开展,其防治已成为热点,近年取得了一定的进展。

Endoscopic retrograde cholangiopancreatography （ERCP） is an important means of diagnosis and treatment of hepatobiliary and pancreatic diseases, especially that the therapeutic ERCP is playing an in- creasingly important role in the minimally invasive treatment of hepatobiliary and pancreatic diseases and is being increasingly applied in clinical practice, ERCP is an invasive technology thus inevitably leads to some complications such as post-ERCP pancreatitis（PEP） which has a high occurrence associated with pancreatic duct developing,difficult intubation, and other factom. Although there are methods to control PEP such as prophylaxis drug before surgery, placing a pancreatic duct stent, and nasobiliary drainage, the occurrence of PEP is still a major problem plaguing clinicians. With the ERCP diagnosis and treatment technology extensive development, PEP prevention has become a hot spot in recent years and has obtained some progress.