结直肠癌并发急性穿孔56例临床治疗分析

A Comparison Study on Colorectal Cancer Complicated with Acute Perforation in 56 Cases

目的探讨结直肠癌并发急性穿孔的临床治疗分析。方法将56例结直肠癌并发急性穿孔患者随机分为观察组(28例)和对照组(28例)。观察组行腹腔镜切除术,对照组行开放式切除术。比较两组患者的手术时间、住院时间、复发率和不良反应等情况。结果观察组患者的手术时间、住院时间少于对照组,复发率和不良反应发生率明显低于对照组,差异有统计学意义(P<0.05)。结论腹腔镜切除术在治疗结直肠癌并发急性穿孔的疗效优于开放式切除术,建议在此类患者中广泛使用。

Objective To compare laparoscopic excision and open surgery for the treatment of colorectal cancer complicated with acute perforation. Methods 56 patients with colorectal cancer complicated with a- cute perforation were randomly divided into observation group （laparoscopic excision group, n = 28 ） and con- trol group（ open surgery group, n = 28 ）. After treatment, the time of surgery and hospitalization, recurrence rates and adverse reactions of the two groups were compared. Results Operative time and hospital stay of the observation group were less than the control group （ P 〈 0.05 ）, the recurrence rate and incidence of adverse reactions of the observation group were significantly lower than the control group（ P 〈 0.05 ）. Conclusion Laparoscopic excision is better than the open surgery for the treatment of colorectal cancer complicated with acute perforation, thus is suggested to be widely used in such patients.