L-天门冬氨酸-β-苄酯的制备研究

Synthesis and characterization of L-aspartic acid-β-benzyl ester

以L-天门冬氨酸和苯甲醇为原料,对L-天门冬氨酸-β-苄酯的合成进行了研究。结果表明,较佳实验条件是:以浓硫酸为催化剂,n(L-天门冬氨酸)∶n(苯甲醇)=1∶10,100℃回流反应3 h,室温放置24 h,在该条件下,产率约60%。

L-aspartic acid and benzyl alcohol as raw materials, studied on the synthesis of L-aspartic β-benzyl ester. The results showed that the best experimental conditions was：the concentrated sulfuric as catalyst,n （L-aspartic acid） ：n （benzyl alcohol） = 1：10,100 ℃ reflux reaction 3 h,placed at temperature 24 h,in this condition,the yield was about 60%.