几种锰盐催化苯甲醛肟重排生成苯甲酰胺的研究

Study on Manganese-Catalyzed Rearrangement of Benzaldoxime into Benzamide

采用4种锰盐MnCl2、Mn(OAc)2、MnO2、MnSO4催化苯甲醛肟重排生成苯甲酰胺。结果表明,Mn(OAc)2具有最高催化效率;以Mn(OAc)2为催化剂,考察了反应温度、催化剂用量和反应时间等因素对产率的影响,确定最佳反应条件为:n[Mn(OAc)2]∶n(苯甲醛肟)=1.1∶10、反应温度110℃、反应时间14h,在此条件下苯甲酰胺产率达66.4%。Mn(OAc)2有效地缩短了反应时间,是一种良好的催化剂。

In this study, four kinds of manganese salts[ MnCl2, Mn（OAc）2, MnO2, MnSO4] were used as catalyst for rearrangement of benzaldoxime into benzamide. The results showed that Mn（OAc）2 had the highest catalytic efficiency. The optimal reaction conditions were obtained as follows= molar ratio of Mn（OAc）e to benzaldoxime of 1. 1 = 10,reaction temperature of 110 ℃,reaction time of 14 h. Under above conditions, the yield of benzamide reached 66.4%. Mn（OAc）2 can effectively shorten the reaction time. Therefore,it is a good catalyst.