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炎症与肿瘤的关系研究进展 被引量:31

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摘要 1863年,Rudolf Virchow观察到肿瘤组织中存在炎症细胞,并首先提出炎症和肿瘤存在关联的假设。慢性炎症和肿瘤之间因果联系的临床证据主要来源于流行病学研究,通过抑制癌前病变患者或肿瘤易感者的慢性炎症,可降低癌症发病和(或)复发的风险[1]。
出处 《国际检验医学杂志》 CAS 2013年第1期63-65,共3页 International Journal of Laboratory Medicine
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  • 1Affara NI,Coussens LM. IKKalpha at the crossroads of inflamma-tion and metastasis[J]. Cell,2007 ,129(1) :25-26.
  • 2Borrello MG, Alberti L,Fischer A,et al. Induction of a proinflam-matory program in normal human thyrocytes by the RET/PTC1oncogene[ J]. Proc Natl Acad Sci USA, 2005,102 ( 41 ): 14825-14830.
  • 3Guerra C,Schuhmacher AJ ,Canamero M.et al. Chronic pancreati-tis is essential for induction of pancreatic ductal adenocarcinomaby K-Ras oncogenes in adult mice[J]. Cancer Cell, 2007,11(3):291-302.
  • 4Balkwill F. Cancer and the chemokine network [J], Nature RevCancer,2004,4(7) :540-550.
  • 5Staller P, Sulitkova J, Lisztwan J, et al. Chemokine receptor CX-CR4 downregulated by von Hippel-Lindau tumour suppressorpVHL[J]. Nature,2003,425(6955) :307-311.
  • 6Helbig G, Christopherson KW 2nd, Bhat-Nakshatri P, et al. NF-kappaB promotes breast cancer cell migration and metastasis byinducing the expression of the chemokine receptor CXCR4 [J], JBiol Chem,2003,278(24) :21631-21638.
  • 7Karin M, Nuclear factor-.cB in cancer development and progression[I]. Nature,2006,441(7092) :431-436.
  • 8Yu H, Kortylewski M, Pardoll D. Crosstalk between cancer andimmune cells:role of STAT3 in the tumour microenvironment[J].Nature Rev Immunol,2007,7(1) :41-51.
  • 9Biswas SK,Gangi L,Paul S,et al. A distinct and unique transcrip-tional program expressed by tumorassociated macrophages : defec-tive NF-kB and enhanced IRF-3/STAT1 activation [ J], Blood.2006,107(5).-2112-2122.
  • 10Apetoh L, Ghiringhelli F, Tesniere A, et al. Toll-like receptor 4-de-pendent contribution of the immune system to anticancer chemothera-py and radiotherapy [J]. Nature Med, 2007,13(9) : 1050-1059.

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