2,4,6-三硝基-2,4,6-三氮杂环己酮的合成研究进展

Progresss in Synthesis of 2,4,6-Trinitro-2,4,6-triazacyclohexanone

汇集、分析、评述了合成2,4,6-三硝基-2,4,6-三氮杂环己酮(Keto-RDX)的方法、途径、特点及原料和硝化体系。附22篇参考文献。认为:以脲和乌洛托品为原料合成Keto-RDX的直接法具有反应步骤少、成本低、产率高的优点和难分离提纯产物的缺点,而通过1,3,5-三嗪类中间体合成Keto-RDX的多步法具有反应步骤多,成本高的缺点和易分离提纯产物的优点。

The strategies, methods, paths, characters, starting materials and nitrating systems of synthesizing 2,4,6-trinitro-2,4,6- triazacyclohexanone（Keto-RDX） were summarized,analysized and reviewed with 22 references. Considering that direct method using urotropine and urea as starting materials has the advantages of less steps,lower cost and higher yield and the disadvantages of difficult separation and purification from a mixtures of Keto-RDX and RDX,while the multistep method of synthesizing Keto-RDX via 1 ,3,5-triazine intermediates has the disadvantages of more reaction steps and higher cost and the advantages of easier separation and purification.