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吗啡肺内吸入对急性冠脉综合征患者剧烈胸痛程度的缓解

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摘要 目的观察吗啡肺内吸入对急性冠脉综合征患者剧烈胸痛的缓解情况。方法将临床确诊为急性冠脉综合征有胸骨后剧烈疼痛的患者40例,随机分为两组,每组20例。A组为实验组,采用吗啡10mg雾化吸入;B组为对照组,采用吗啡5mg静脉注射。结果两组患者胸痛均明显缓解,比较差异无统计学意义(P>0.05)。A组较B组发生恶心、呕吐及呼吸抑制患者明显减少(P<0.05)。结论吗啡雾化吸入用于急性冠脉综合征剧烈胸痛患者,能有效地缓解胸痛,且副作用较静脉注射发生率小。
作者 秦维 易晓淑
出处 《中西医结合心脑血管病杂志》 2013年第1期113-113,共1页 Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
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参考文献7

  • 1刘继霞.急性心肌梗死早期的康复处理[J]中外健康文摘,2011(08):167-168.
  • 2王建华.药理学[M]深圳:海天出版社,198998-99.
  • 3潘琳,汪小海.吗啡雾化吸入给药的研究进展[J].药学与临床研究,2007,15(5):341-343. 被引量:3
  • 4Ward ME,Woodhouse A,Mather LE. Morphine pharmacokinetis after pulmonary administration fromanovel aerosol delivery system[J].Clinical Pharmacology and Therapeutics,1997,(06):596-609.
  • 5Dershwitz M,Walsh,Morishige RJ. Pharmacokinetics and pharmacodynamics of inhaled versus intravenous morphine in healthy volunteers[J].Anesthesiology,2000,(03):619-628.
  • 6Ballas SK,Viscusi ER,Epstein KR. Management of acute chest wall sickle cell pain with nebulized morphine[J].Am Hernatof,2004,(02):190-191.
  • 7Thipphawong JB,Babul N,Morishige RJ. Analgesic efficacy of in haled morphine in patients after bunionectomy surgery[J].Anesthesiology,2003,(03):693-700.

二级参考文献18

  • 1Chrubasik J,Wust H,Friedrich G,et al.Absorption and bioavailability of nebulized morphine[J].Br J Anaesth,1988,61(2):228-230.
  • 2Masood AR,Thomas SH.Systemic absorption of nebulized morphine compared with oral morphine in healthy subjects[J].Br J Clin Pharmacol,1996,41(3):250-252.
  • 3Schuster J,Rubsamen R,Lloyd P,et al.The AERxTM aerosol delivery system[J].Pharma Res,1997,14(3):354-357.
  • 4Ward ME,Woodhouse A,Mather LE,et al.Morphine pharmacokinetics after pulmonary administration from a novel aerosol delivery system[J].Clin Pharmacol Ther,1997,62(6):596-609.
  • 5Dershwitz M,Walsh JL,Morishige RJ,et al.Pharmacokinetics and pharmacodynamics of inhaled versus intravenous morphine in healthy volunteers[J].Anesthesiology,2000,93(3):619-628.
  • 6Doenicke A,Moss J,Lorenz W,et al.Intravenous morphine and nalbuphine increase histamine and catecholamine release without accompanying hemodynamic changes[J].Clin Pharmacol Ther,1995,58(1):81-89.
  • 7Withington DE,Patrick JA,Reynolds F.Histamine release by morphine and diamorphine in man[J].Aneasthesia,1993,48(1):26-29.
  • 8Lang E,Jedeikin R.Acute respiratory depression as a complication of nebulized morphine[J].Can J Anaesth,1998,45(1):60-62.
  • 9Otulana B,Okikawa J,Linn L,et al.Safety and pharmacokinetics of inhaled morphine delivered using the AERx system in patients with moderate-to-severe asthma[J].Int J Clin Pharmacol Ther,2004,42(8):456-462.
  • 10Farncombe M,Chater S.Case studies outlining use of nebulized morphine for patients with end-stage chronic lung and cardiac disease[J].J Pain Symptom Manage,1993,8(4):221-225.

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