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阻塞性睡眠呼吸暂停低通气综合征与氧化抗氧化的相关性 被引量：4

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摘要 目的观察阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者及OSAHS相关高血压(OSAHAHT)患者血清氧化低密度脂蛋白(ox-LDL)及血清对氧磷酶(PON)水平的变化。方法选择OSAHS及OSAHAHT患者各20例及健康对照组20例,应用酶联免疫吸附试验检测血清ox-LDL及PON水平,并与睡眠监测指标进行相关分析。结果与对照组比较OSAHS及OSAHAHT患者血清ox-LDL浓度升高,PON浓度降低(P<0.01)。OSAHS及OSAHAHT患者血清ox-LDL、PON水平与反映睡眠呼吸暂停严重程度的指标有相关性(P<0.01)。结论 OSAHS及OSAHAHT患者存在血清ox-LDL及PON水平变化,存在氧化应激,血清ox-LDL及PON水平可以反映OSAHS患者的氧化应激严重程度。
作者 高爱武 韩丽娟 高淑磊 田玉静 平芬
机构地区 保定市第二医院呼吸科 河北省人民医院
出处 《中国老年学杂志》 CAS CSCD 北大核心 2013年第2期317-319,共3页 Chinese Journal of Gerontology
关键词 阻塞性睡眠呼吸暂停低通气综合征 氧化低密度脂蛋白 对氧磷酶 高血压 氧化抗氧化
分类号 R56 [医药卫生—呼吸系统]
  • 相关文献

参考文献11

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共引文献2401

同被引文献32

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二级引证文献11

中国老年学杂志
2013年 第2期

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