肥胖人群腹部脂肪含量与阻塞性睡眠呼吸暂停综合征的关系

The relationship between abdominal fat volume and obstructive sleep apnea hypopnea syndrome in obesity people

目的探讨在国人体重过重者（BMI〉25）中，阻塞型睡眠呼吸暂停综合征（OSAHS）患者与非OSAHS患者腹部脂肪含量的区别，及腹部脂肪对OSAHS的影响。方法对北京朝阳医院呼吸内科2009年7月至2010年7月收治的主诉打鼾患者中BMI〉25的病例进行前瞻性研究，共25例，为OSAHS组（病例组），另征集无打鼾主诉，BMI〉25的志愿者30例，为非OSAHS组（对照组）。对2组均进行睡眠呼吸监测诊断及全腹部CT影像学检查，CT三维重建系统测量全腹部脂肪体积。数据采用SPSS13．0统计软件处理。结果病例组与对照组腹部脂肪含量经采用t检验进行组间比较，病例组的腹部脂肪含量明显高于对照组（P〈0．01），OSAHS与腹部脂肪含量的关系有统计学意义。结论肥胖人群中，OSAHS与腹部脂肪含量的关系密切，体重过重者，OSAHS患者的腹部脂肪含量明显高于对照组。

Objective To explore the relationship between abdominal fat volume and obstructive sleep apnea hypopnea syndrome in obesity people. Methods From July 2009 to July 2010, 50 patients with BMI 〉 25 were prospectively selected for study from the patients who complained of snoring in the Respiratory department. The patients were divided into OSAHS group and non-OSAHS group according to the result of sleep apnea monitoring. All the patients also received full abdominal CT and the whole abdominal fat volume was measured by 3-D CT reconstruction system. SPSS 13.0 was used for statistical analysis. Results The whole abdominal fat volume in the two groups was analyzed by T- test, which was significantly different between the two groups（P 〈 0.01 ）. It showed that there was a statistical relationship between OSAHS and abdominal fat in obesity people. Conclusions In obesity people, OSAHS has a close relationship with abdominal fat volume. The abdominal fat volume is markedly higher in OSAHS patients than that in non-OSAHS people.