斑点追踪成像技术对心功能不全患者心肌应变及收缩不同步性的评价

Evaluation of cardiac muscle strain and systolic dyssynchrony in patients with cardiac insufficiency by speckle tracking imaging

收集30例心功能不全患者和30例健康志愿者的左室短轴二尖瓣、乳头肌及心尖水平和心尖四腔、心尖两腔及心尖左室长轴的二维灰阶图像,测量各节段心肌应变峰值及应变达峰时间,计算达峰时间最大差值及标准差,同时应用实时三平面左室容积法测量左室射血分数(LVEF)。结果显示心功能不全组心肌纵向、径向及圆周应变较对照组降低(P<0.05),达峰时间不一致;左室收缩不同步指数均较对照组显著延长(P<0.01)。径向不同步指数与LVEF相关性较高。

This research used standard dynamic images of basal, papillary muscle and apical - LV short-axis from thirty patients with cardiac insufficiency and thirty healthy volunteers, meanwhile, apical long axis chamber, 4 chamber and 2 chamber views of three consecutive cardiac cycles were acuquired. Parameters included peak systol- ic strain, the maximum difference and standard deviation of time to peak systolic strain （Txs-diff, Txs-SD） among 18 segments were measured and calculated. Simultaneously, left ventricular ejection fraction（LVEF） was calculat- ed through real time tri-plane LV volume rule. Compared with healthy volunteers, the longitudinal, radial and cir- cumferential peak strian were reduced in patients with cardiac insufficiency （ P 〈 0. 05 ） , the time to peak strian was inconsistent; Left ventricular systolic dyssynchrony indices （SDI） were prolonged significantly（P 〈 0. 01 ）. There were a higher correlation between radial indices and LVEF.