深圳市罗湖区疑似预防接种异常反应监测及处置机制研究

To Analyze the Characteristics and Categories of Adverse Events Following lmmunization(AEFI) in Luohu District,Shenzhen City

目的分析深圳市罗湖区疑似预防接种异常反应(AEFI)分类及特征,根据《预防接种异常反应鉴定办法》及《广东省预防接种异常反应补偿办法(试行)》及实施细则规定,结合深圳市罗湖区AEFI处理结果,形成深圳市罗湖区AEFI处置机制。方法通过中国免疫规划监测信息管理系统,收集全区报告的2009—2011年AEFI个案及处置方法,采用描述性方法对相关指标进行分析。结果 2009—2011年共报告AEFI病例195例,2010年、2011年AEFI报告发生率在1.00/10万～1.05/10万的范围内,2009年AEFI报告发生率大幅上升,达到12.66/10万。AEFI分类诊断中,一般反应占49.23%,异常反应占47.18%,其他占3.59%,各种监测指标年报及时率逐年上升。结论建立完善的疫苗不良反应报告和处置机制,是扩大免疫规划工作成功的关键。

OBJECTIVE To analyze the characteristics and categories of adverse Events Following Immunization（AEFI） in Luohu District, Shenzhen City, form a AEFI disposal mechanism based on related guiding documents. METHOD Descriptive epidemiology was adopted to analyze the indexes, AEFI cases in Luohu District from 2009 to 2011, collected from the China immunization monitoring information management system. RESULTS The reported AEFI cases were 195 from 2009 to 2011. And the reported incidence rate of AEFI cases was 12.66/100 000 in 2009, then in the following two years decreased to 1.00/100 000-1.05/100 000. In all AEFI cases, 49,23% cases were common, minor reactions, 47.18% were rare, the rest types stood for 3.59 percent. Timely report rate increased yearly. CONCLUSIONS A comprehensive AEFI report and disposal mechanism was guarantee for expanded programme on immunization.