不同材质的医疗物品环氧乙烷灭菌后残留量监测分析

Analysis of Ethylene Oxide Residue Level of Sterilized Medical Supplies with Different Raw Materials

目的:经环氧乙烷灭菌后,对不同材质的医疗物品在相同时间内的环氧乙烷残留量进行监测分析,以确保环氧乙烷灭菌后物品的安全使用。方法:实验材料选用手术室常用的压迫止血袖带、螺纹呼吸机管、硅胶胃管。用纸塑包装卷料包装后经环氧乙烷灭菌,按平行取样法取样,利用气相色谱对每一时段样品进行环氧乙烷残留量的测定。结果:不同材质的医疗物品经环氧乙烷灭菌后在相同的时间内环氧乙烷残留量不同,止血袖带(棉布类材料)对环氧乙烷气体有很强的吸附性,残留量很难彻底解析,所以对此类产品不宜选用环氧乙烷灭菌。结论:了解环氧乙烷的残留毒性和准确测定灭菌物品中环氧乙烷残留量,对于其灭菌后物品安全使用非常重要。

Objective To ensure the safe use of medical supplies after sterilization by ethylene oxide by monitoring the amount of ethylene oxide residues of the different materials at the same time. Methods The compression hemostasis cuff, thread ventilator tube and silicone tube were selected as the experimental materials. Ethylene oxide sterilization was performed after packaging the supplies with paper plastic materials, and then parallel sampling and residue level analysis by meteorological chromatography were executed.Results The supplies had different residue levels after ethylene oxide sterilization, of which, compression hemostasis cuff made of cotton could absorb ethylene oxide strongly and was not fit for ethylene oxide sterilization. Conclusion To analyze the residue level of ethylene oxide is very important for the safety of the sterilized medical supplies.