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分子氢——医学气体研究的新视角 被引量：3

Molecular hydrogen——a novel perspective of medical gas research
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摘要 医学气体在临床中有着广泛的应用,以往被认为是生理性惰性气体的氢气(H2),最近研究表明它不仅具有抗氧化作用,同时具有抗炎和抗细胞凋亡作用,在缺血再灌注损伤、动脉粥样硬化、代谢综合征等多种系统性疾病中发挥保护作用,其生物学意义值得深入研究,并可能启动了一种新的生物医学研究领域。 Medical gas has been widely used in clinical practice. Previously considered to be a physiological inertgas, hydrogen, not only has anti-oxidation effect, but also has anti-inflammatory and viates ischemia-reperfusion injury, atherosclerosis, metabolic syndrome and other sys anti-apoptotic effect, temic diseases. The and alle- biological effect of hydrogen gas is worth to be further investigated, and is a potential novel field of biomedical research.
作者 王新宝 崔红
机构地区 首都医科大学附属北京友谊医院儿科
出处 《基础医学与临床》 CSCD 北大核心 2013年第2期249-252,共4页 Basic and Clinical Medicine
关键词 氢气 缺血再灌注损伤 动脉粥样硬化 hydrogen gas ischemic reperfusion atherosclerosis
分类号 R363 [医药卫生—病理学]
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参考文献25

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同被引文献32

  • 1Jinghu He,Shaohu Xiong,Jianquan Zhang,Junwu Wang,Aijun Sun,Xiang Mei,Xuejun Sun,Chuansen Zhang,Qiang Wang.Protective effects of hydrogen-rich saline on ulcerative colitis rat model[J].Journal of Surgical Research.2013
  • 2Shigeo Ohta.Molecular hydrogen is a novel antioxidant to efficiently reduce oxidative stress with potential for the improvement of mitochondrial diseases[J].BBA - General Subjects.2011(5)
  • 3Han Chen,Yan Ping Sun,Ping Fang Hu,Wen Wu Liu,Hong Gang Xiang,Yang Li,Rong Lin Yan,Ning Su,Can Ping Ruan,Xue Jun Sun,Qiang Wang.The Effects of Hydrogen-Rich Saline on the Contractile and Structural Changes of Intestine Induced by Ischemia-Reperfusion in Rats[J].Journal of Surgical Research.2011(2)
  • 4Chien-Sheng Huang,Tomohiro Kawamura,Yoshiya Toyoda,Atsunori Nakao.Recent advances in hydrogen research as a therapeutic medical gas[J].Free Radical Research.2010(9)
  • 5Yan-Fei Mao,Xing-Feng Zheng,Jian-Mei Cai,Xin-Min You,Xiao-Ming Deng,John H. Zhang,Lai Jiang,Xue-Jun Sun.Hydrogen-rich saline reduces lung injury induced by intestinal ischemia/reperfusion in rats[J].Biochemical and Biophysical Research Communications.2009(4)
  • 6Sizuo Kajiyama,Goji Hasegawa,Mai Asano,Hiroko Hosoda,Michiaki Fukui,Naoto Nakamura,Jo Kitawaki,Saeko Imai,Koji Nakano,Mitsuhiro Ohta,Tetsuo Adachi,Hiroshi Obayashi,Toshikazu Yoshikawa.Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance[J].Nutrition Research.2008(3)
  • 7Bouchra Gharib,Stéphane Hanna,Ould M.S. Abdallahi,Hubert Lepidi,Bernard Gardette,Max De Reggi.Anti-inflammatory properties of molecular hydrogen: investigation on parasite-induced liver inflammation[J].Comptes Rendus de l’Academie des Sciences Series III Sciences de la Vie.2001(8)
  • 8Ruth Simpson,Rafael Alon,Lester Kobzik,C. Robert Valeri,David Shepro,Herbert B. Hechtman.Neutrophil and Nonneutrophil-Mediated Injury in Intestinal Ischemia-Reperfusion[J].Annals of Surgery.1993(4)
  • 9周军,黄文起,李偲,吴贵云,李云胜,温仕宏,雷万龙,刘克玄.肠缺血再灌注对大鼠脑的影响[J].中华麻醉学杂志,2011,31(6):739-742. 被引量：4
  • 10任汉强,沈小波.氢气饱和生理盐水对高糖所致内皮细胞内活性氧生成和凋亡的影响[J].重庆医学,2012,41(6):575-577. 被引量：4

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基础医学与临床
2013年 第2期

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