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紫杉类药物在前列腺癌治疗中的进展和意义 被引量:2

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摘要 前列腺癌是威胁男性健康的常见肿瘤之一,其发病呈现地区和种族差异。与发达国家相比,中国的前列腺癌发病率较低,但近年来发病率逐年增高,且初诊时多为疾病晚期。内分泌治疗(例如手术和 药物去势、雄激素受体拮抗剂及其他抗雄激素药物)是晚期前列腺癌的主要治疗手段,但几乎所有初始内分泌敏感的患者最终都将发展为去势抵抗性前列腺癌(CRPC)。此时内分泌治疗虽有助于改善相关症状,但大多不能控制疾病的进展。因此,CRPC是前列腺癌治疗中的重点和难点,迫切需要引入其他有效的治疗方法。
作者 叶定伟
出处 《中华医学杂志》 CAS CSCD 北大核心 2013年第4期241-242,共2页 National Medical Journal of China
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