超声造影诊断甲状腺乳头状癌可行性研究

Application of contrast-enhanced ultrasound in the diagnosis of papillary thyroid carcinoma

目的:探讨超声造影(CEUS)诊断甲状腺乳头状癌(PTC)的可行性。方法:对51例超声疑似PTC的患者,术前经灰阶及CDFI检查后行CEUS检查,动态观察微泡在病灶灌注的全过程、灌注模式及边缘灌注情况。结果:PTC结节大小与超声造影表现有显著相关性(P<0.001),始增时间、峰值时间在正常甲状腺组织与PTC组织有显著差异(P<0.001),但边缘增强和消退时间并无此发现(P>0.05)。结论:灌注缺损、淡淡弱灌注及不均匀增强三种灌注模式在一定程度上提示PTC,较常规灰阶超声能更早、更敏感地评价PTC乏血供灌注特征。

Objective：To explore the value of contrast - enhanced ultrasound（CEUS） in the diagnosis of papillary thyroid carcinoma（VFC）. Methods： Fifty one cases were included in this study. All the PTC lesions underwent examinations of CEUS. The type of time - intensity curves （ TIC ） was analyzed by TomTee software. Results ： All PTC showed perfusion defects was a touch weak imaging（ P 〈 0. 001 ）, non -uniform enhancement, increase time lesions began later than the surrounding thyroid tissue （ P 〈 0.001 ） , fade time showed no difference （ P 〉 0.05 ）. Conclusion： Perfusion defects, faint weak and uneven increase of papillary thyroid carcinoma after contrast - enhanced ultrasound can provide important supplement to diagnosis and may further improve the diagnostic accuracy for PTC.