摘要
目的:分析三阴性乳腺癌的临床病理特征和预后影响因素。方法:选取219例具有完整随访结果的浸润性乳腺癌病例,按ER、PR、HER-2表达情况分为三阴性亚群和非三阴性亚群。结果:三阴性亚群中髓样癌及组织学分级3级者所占比例显著高于非三阴性亚群,随访期间,两组患者的复发转移率、无病生存率及总生存率无显著差异。生存分析提示淋巴结状态是三阴性亚群预后的独立影响因素。结论:三阴性乳腺癌的组织学分级高于非三阴性乳腺癌,淋巴结转移状态是三阴性亚群预后的独立影响因素。
Objective :To investigate the clinieopathological ieatures and prognostic tactors m patmnts wire mpm negative breast cancer. Methods :Total of 219 cases with complete follow -up data were categorized into triple nega- tive breast cancer(TNBC) and non -triple negative breast cancer( non -TNBC). Results: In this cohort,69 patients were TNBC. The rates of medullary carcinoma and pathological grade m in TNBC were higher than in those of the non - TNBC. During the follow - up period, no significant differences in prognosis were found between these two subgroups. By univariate and multivariate survival analysis, node status was demonstrated as the independent prognostic factors for TNBC. Conclusion:Patients with TNBC showed higher pathological grade, and node status was demonstrated as the independent prognostic factor for TNBC.
出处
《现代肿瘤医学》
CAS
2013年第2期294-298,共5页
Journal of Modern Oncology
基金
陕西省科技计划项目(编号:S2010SF855)
关键词
三阴性乳腺癌
临床病理特征
预后
triple negative breast cancer
clinicopathological feature
prognosis