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1,25(OH)_2D_3对6T-CEM细胞株维生素D受体表达的作用研究 被引量：1

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摘要 除了经典的调节钙磷代谢外，1，25二羟基维生素D（1，25（OH）2D3）及其类似物还具有抗增殖、促分化、促进肿瘤凋亡等作用。本研究以人急性T淋巴细胞白血病细胞株6T-CEM为研究对象，观察1，25（OH）2D3作用前后维生素D受体（vitamin Dreceptor，VDR）mRNA和蛋白表达的变化，探讨其抗白血病的分子机制及用于白血病治疗的可行性。
作者 郑敏 何云燕 罗建明
机构地区 柳州市妇幼保健院儿内科 广西医科大学第一附属医院儿科
出处 《临床荟萃》 CAS 2013年第2期186-187,共2页 Clinical Focus
关键词 白血病 T细胞 急性 受体 骨化三醇 荧光抗体技术 印迹法 蛋白质
分类号 R733.7 [医药卫生—肿瘤]
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参考文献12

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同被引文献15

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临床荟萃
2013年 第2期

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